Publications
2025
■ Kim H, Kim H, Jang E, Eom YW, Yoon G, Choi KS, Kim E*. Dual role of p21 in regulating apoptosis and mitotic integrity in response to doxorubicin in colon cancer cells. Cell Death Discovery. 2025 Apr 2;11(1):133.
■ Jang JH, Kim H, Jun H, Park CY, Kim JY, Yeo M, Kim H, Shin Y, Kang S, Kim E*, Lee TJ*. Targeting RBM39 with Tasisulam enhances TRAIL-induced apoptosis through DR5 upregulation and Bcl-2 downregulation in renal cell carcinoma.
Biochemical Pharmacology. 2025 Jun 1;236:116877.
■ Lee J, Kim H, Yeo M, Kim H, Lee E, Kim H, Park Y, Jang E, Choi KS, Kim E*. SUN2 downregulation promotes breast cancer cell proliferation via NFATC4 upregulation. Biochemical and Biophysical Research Communications. 2025 Nov 25:153047.
2024
■ Lee DM, Kim IY, Lee HJ, Seo MJ, Cho MY, Lee HI, Yoon G, Ji JH, Park SS, Jeong SY, Yeo M, Kim E*, Choi KS*. Akt enhances the vulnerability of cancer cells to VCP/p97 inhibition-mediated paraptosis. Cell Death & Disease. 2024 Jan 13;15(1):48.
■ Jun H, Yeo M, Jeon JP, Eom S, Kim HJ, Kim Y, Jang E, Park SH, Kim E*, Kang S*. CD13-targeting and TRAIL-displaying protein nanoparticles effectively induce apoptotic cell death of acute myeloid leukemia, prolonging survival in mouse models.
Nano Today. 2024 Dec 1;59:102474.
2023
■ Kang Y, Yeo M, Choi H, Jun H, Eom S, Park SG, Yoon H, Kim E*, Kang S*. Lactate oxidase/vSIRPα conjugates efficiently consume tumor-produced lactates and locally produce tumor-necrotic H2O2 to suppress tumor growth.
International Journal of Biological Macromolecules. 2023 Mar 15;231:123577.
■ Choi H, Yeo M, Kang Y, Kim HJ, Park SG, Jang E, Park SH, Kim E*, Kang S*. Lactate oxidase/catalase-displaying nanoparticles efficiently consume lactate in the tumor microenvironment to effectively suppress tumor growth.
Journal of nanobiotechnology. 2023 Jan 3;21(1):5.
2022
■ Jun H, Jang E, Kim H, Yeo M, Park SG, Lee J, Shin KJ, Chae YC, Kang S*, Kim E*. TRAIL & EGFR affibody dual-display on a protein nanoparticle synergistically suppresses tumor growth. Journal of Controlled Release. 2022 Sep 1;349:367-78.
■ Park SG, Kim H, Jun H, Choi SY, Kim E*, Kang S*. Directing ricin-based immunotoxins with targeting affibodies and KDEL signal peptide to cancer cells effectively induces apoptosis and tumor suppression. Journal of nanobiotechnology. 2022 Aug 23;20(1):387.
■ Clough CA, Pangallo J, Sarchi M, Ilagan JO, North K, Bergantinos R, Stolla MC, Naru J, Nugent P, Kim E, Stirewalt DL. Coordinated missplicing of TMEM14C and ABCB7 causes ring sideroblast formation in SF3B1-mutant myelodysplastic syndrome.
Blood, The Journal of the American Society of Hematology. 2022 Mar 31;139(13):2038-49.
2021
■ Kim E, Lee DM, Seo MJ, Lee HJ, Choi KS. Intracellular Ca²⁺ imbalance critically contributes to paraptosis.
Frontiers in cell and developmental biology. 2021 Jan 12;8:607844.
2020
■ Jang E, Kim IY, Kim H, Lee DM, Seo DY, Lee JA, Choi KS*, Kim E*. Quercetin and chloroquine synergistically kill glioma cells by inducing organelle stress and disrupting Ca2+ homeostasis. Biochemical Pharmacology. 2020 Aug 1;178:114098.
2019
■ Oh JM, Kim E, Chun S. Ginsenoside compound K induces ros-mediated apoptosis and autophagic inhibition in human neuroblastoma cells in vitro and in vivo. International journal of molecular sciences. 2019 Sep 1;20(17):4279.
2018
■ Lee SC, North K, Kim E, Jang E, Obeng E, Lu SX, Liu B, Inoue D, Yoshimi A, Ki M, Yeo M. Synthetic lethal and convergent biological effects of cancer-associated spliceosomal gene mutations. Cancer cell. 2018 Aug 13;34(2):225-41.
2017
■ Durham BH, Getta B, Dietrich S, Taylor J, Won H, Bogenberger JM, Scott S, Kim E, Chung YR, Chung SS, Hüllein J. Genomic analysis of hairy cell leukemia identifies novel recurrent genetic alterations.
Blood, The Journal of the American Society of Hematology. 2017 Oct 5;130(14):1644-8.
■ Micol JB, Pastore A, Inoue D, Duployez N, Kim E, Lee SC, Durham BH, Chung YR, Cho H, Zhang XJ, Yoshimi A. ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia. Nature communications. 2017 May 18;8(1):15429.